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Catalyst Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on developing and commercializing medicines for patients living with rare diseases in the United States. It offers Firdapse for the treatment of patients with lambert-eaton myasthenic syndrome (LEMS); Fycompa, a novel non-competitive selective antagonist at the postsynaptic ionotropic alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid glutamate receptor that is used to treat focal onset seizures, as well as tonic-clonic seizure; and AGAMREE, a corticosteroid for the treatment of duchenne muscular dystrophy. The company has license agreements with BioMarin Pharmaceutical Inc.; and a collaboration and license agreement with Endo Ventures Limited for the development and commercialization of generic Sabril tablets. Catalyst Pharmaceuticals, Inc. was founded in 2002 and is based in Coral Gables, Florida.
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Catalyst Pharmaceuticals develops and commercializes therapies for rare neuromuscular disorders and is best known for Firdapse (amifampridine) for Lambert-Eaton myasthenic syndrome in the U.S. Long-term growth may be supported by orphan-drug pricing, potential label expansions or geographic rollout, and further scaling of specialty sales and reimbursement capabilities, which could support steady revenue from a defined patient population. Investors may find exposure to a commercial orphan drug with an established U.S. presence of interest.
Key risks include heavy reliance on a single marketed product with a small patient base, exposure to reimbursement and pricing pressure, the threat of generic or compounded alternatives, and regulatory or legal setbacks that could materially affect revenues.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | 283.51M | 216.26M | 94.51M | 104.72M | 52.67M |
| Net income | 214.33M | 163.89M | 71.41M | 83.08M | 39.48M |
| Selling general administrative | 193.75M | 167.74M | 47.02M | 28.71M | 23.48M |
| Selling and marketing expenses | - | 10.00M | 86.69M | 29.47M | 26.15M |
| Gross profit | 501.74M | 422.89M | 346.24M | 179.81M | 118.95M |
| Reconciled depreciation | 37.87M | 37.77M | 24.35M | 1.24M | 0.19M |
| Ebit | 283.51M | 195.12M | 86.81M | 100.60M | 52.19M |
| Ebitda | 321.01M | 232.90M | 119.69M | 101.84M | 52.38M |
| Depreciation and amortization | 37.50M | 37.77M | 32.88M | 1.24M | 0.19M |
| Non operating income net other | - | - | - | 2.88M | 0.28M |
| Operating income | 257.78M | 195.12M | 86.81M | 101.84M | 52.38M |
| Other operating expenses | 331.21M | 296.61M | 311.39M | 112.36M | 88.45M |
| Interest expense | - | - | - | -4.12M | 0.47M |
| Tax provision | 69.19M | 52.37M | 18.77M | 21.64M | 13.19M |
| Net interest income | 24.77M | 16.06M | 4.67M | - | - |
| Income tax expense | 69.19M | 52.37M | 23.10M | 21.64M | 13.19M |
| Total revenue | 588.99M | 491.73M | 398.20M | 214.20M | 140.83M |
| Total operating expenses | 243.96M | 227.76M | 259.43M | 77.97M | 66.56M |
| Cost of revenue | 87.25M | 68.84M | 51.97M | 34.39M | 21.88M |
| Total other income expense net | 25.74M | 21.14M | 7.70M | 2.88M | 0.28M |
| Net income from continuing ops | 214.33M | 163.89M | 62.04M | 83.08M | 39.48M |
| Net income applicable to common shares | - | - | - | 83.08M | 39.48M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 1106.81M | 851.41M | 471.91M | 375.63M | 237.79M |
| Intangible assets | 131.67M | 156.67M | 194.05M | 32.47M | - |
| Other current assets | 19.43M | 21.03M | 12.54M | 5.16M | 4.35M |
| Total liab | 152.54M | 123.78M | 84.03M | 75.21M | 30.96M |
| Total stockholder equity | 954.27M | 727.63M | 387.88M | 300.42M | 206.83M |
| Other current liab | 135.51M | 102.79M | 60.17M | 53.28M | 0.24M |
| Common stock | 0.12M | 0.12M | 0.11M | 0.10M | 0.10M |
| Capital stock | 0.12M | 0.12M | 0.11M | 0.10M | 0.10M |
| Retained earnings | 474.19M | 285.16M | 121.27M | 49.86M | -26.31M |
| Other liab | - | - | - | 14.06M | - |
| Other assets | - | - | 0.00M | 18.75M | 23.71M |
| Cash | 709.17M | 517.55M | 137.64M | 298.39M | 171.44M |
| Total current liabilities | 147.15M | 120.68M | 76.06M | 57.59M | 27.06M |
| Current deferred revenue | - | - | 0.73M | - | 23.74M |
| Net debt | -706.38M | -514.37M | -134.08M | -294.50M | -167.55M |
| Short term debt | 0.44M | 0.40M | 0.37M | 0.34M | 0.31M |
| Short long term debt total | 2.79M | 3.19M | 3.56M | 3.89M | 3.89M |
| Other stockholder equity | 479.96M | 442.29M | 266.49M | 250.43M | 233.19M |
| Property plant equipment | - | - | - | 0.85M | 3.98M |
| Total current assets | 894.03M | 623.61M | 219.33M | 320.80M | 210.11M |
| Long term investments | 22.54M | 21.56M | 16.49M | - | - |
| Net tangible assets | - | - | - | 267.95M | 206.83M |
| Short term investments | - | - | - | 0.00M | 19.82M |
| Net receivables | 128.27M | 65.49M | 53.51M | 10.44M | 6.62M |
| Inventory | 37.17M | 19.54M | 15.64M | 6.80M | 7.87M |
| Accounts payable | 11.20M | 16.59M | 14.79M | 3.98M | 2.77M |
| Accumulated other comprehensive income | - | 0.06M | 0.01M | 0.02M | -0.15M |
| Common stock total equity | - | - | - | 0.10M | 0.10M |
| Retained earnings total equity | - | - | - | 49.86M | -26.31M |
| Non currrent assets other | - | - | -0.00M | 0.01M | 0.01M |
| Non current assets total | 212.78M | 227.80M | 252.58M | 54.83M | 27.68M |
| Capital lease obligations | 2.79M | 3.19M | 3.56M | 3.89M | 3.89M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | 0.00M | -0.56M | -255.18M | 19.24M | -10.00M |
| Change to liabilities | - | - | - | 17.60M | 4.03M |
| Total cashflows from investing activities | -0.06M | -0.56M | - | 9.21M | -11.02M |
| Total cash from financing activities | -16.99M | 140.66M | -10.86M | 1.69M | -8.14M |
| Change to operating activities | - | - | - | 15.28M | 10.36M |
| Net income | 214.33M | 163.89M | 71.41M | 83.08M | 39.48M |
| Change in cash | 191.62M | 379.92M | -160.76M | 126.95M | 41.21M |
| Begin period cash flow | 517.55M | 137.64M | 298.39M | 171.44M | 130.24M |
| End period cash flow | 709.17M | 517.55M | 137.64M | 298.39M | 171.44M |
| Total cash from operating activities | 208.67M | 239.81M | 143.60M | 116.05M | 60.37M |
| Issuance of capital stock | 0.00M | 141.00M | - | - | - |
| Depreciation | 37.87M | 37.77M | 33.14M | 1.24M | 0.19M |
| Other cashflows from investing activities | - | 13.14M | - | -10.00M | - |
| Change to inventory | -18.09M | -3.90M | -4.74M | 1.06M | -3.22M |
| Change to account receivables | -61.00M | -11.96M | -43.08M | -3.82M | -0.63M |
| Sale purchase of stock | -25.30M | -0.30M | -0.98M | -6.91M | -12.09M |
| Other cashflows from financing activities | -6.36M | -0.04M | -13.65M | 4.50M | -0.15M |
| Change to netincome | - | - | - | 12.84M | 15.39M |
| Capital expenditures | 0.06M | 0.56M | 198.52M | 0.03M | 1.02M |
| Change receivables | - | - | - | -3.82M | -0.63M |
| Cash flows other operating | - | - | - | 4.04M | 5.13M |
| Cash and cash equivalents changes | - | - | - | 126.95M | 41.21M |
| Change in working capital | -60.90M | 30.91M | -37.32M | 13.73M | 5.02M |
| Stock based compensation | 24.78M | 22.25M | 14.25M | 7.91M | 6.07M |
| Other non cash items | -0.56M | -5.63M | 79.94M | 5.16M | 0.29M |
| Free cash flow | 208.61M | 239.25M | -54.92M | 116.02M | 59.35M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| NVO Novo Nordisk A/S |
-0.54 1.32% |
40.55 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
-2.37 0.43% |
544.66 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
-2.77 0.29% |
956.64 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
Catalyst Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on developing and commercializing medicines for patients living with rare diseases in the United States. It offers Firdapse for the treatment of patients with lambert-eaton myasthenic syndrome (LEMS); Fycompa, a novel non-competitive selective antagonist at the postsynaptic ionotropic alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid glutamate receptor that is used to treat focal onset seizures, as well as tonic-clonic seizure; and AGAMREE, a corticosteroid for the treatment of duchenne muscular dystrophy. The company has license agreements with BioMarin Pharmaceutical Inc.; and a collaboration and license agreement with Endo Ventures Limited for the development and commercialization of generic Sabril tablets. Catalyst Pharmaceuticals, Inc. was founded in 2002 and is based in Coral Gables, Florida.
355 Alhambra Circle, Coral Gables, FL, United States, 33134
305 420 3200
182
| Name | Title | Year Born |
|---|---|---|
| Mr. Patrick J. McEnany | Co-Founder, Chairman, Pres & CEO | 1947 |
| Ms. Alicia Grande C.M.A., CPA, CMA, CPA | Chief Accounting Officer, VP, Treasurer & CFO | 1971 |
| Dr. Steven R. Miller Ph.D. | COO & Chief Scientific Officer | 1962 |
| Dr. Gary Ingenito M.D., Ph.D. | Chief Medical & Regulatory Officer | 1956 |
| Dr. Preethi Sundaram Ph.D. | Chief Strategy Officer | 1976 |
| Ms. Mary Coleman | VP & Head of Investor Relations | NA |
| Mr. Brian Elsbernd J.D. | Chief Compliance Officer & Chief Legal Officer | 1964 |
| Mr. Pete Curry Sr. | VP of Sales | NA |
| Mr. Jeffrey Del Carmen | Chief Commercial Officer | 1971 |
| Mr. Philip B. Schwartz | Corp. Sec. | 1955 |
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