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Prothena Corporation plc, a late-stage clinical biotechnology company, focuses on discovery and development of novel therapies to treat diseases caused by protein dysregulation. Its product pipeline includes Prasinezumab, an investigational humanized monoclonal antibody which is in Phase 3 clinical trial for the treatment of parkinson's disease and other synucleinopathies. The company also develops Coramitug, an investigational antibody, which is in Phase 3 clinical trial for the treatment of transthyretin amyloidosis; BMS-986446, an anti-tau antibody which is in Phase 2 clinical trial to treat Alzheimer's disease; PRX019, an investigational antibody which is in Phase 1 clinical trial for the treatment of neurodegenerative diseases; and PRX123, a Dual Aß-Tau Vaccine, which is in preclinical trial for treating Alzheimer's disease. In addition, it develops discovery- and late-preclinical-stage programs include TDP-43 CYTOPE for the treatment of amyotrophic lateral sclerosis; PRX012, a next-generation anti-Aß antibody which is in phase 1 clinical trial to treat Alzheimer's disease; and PRX012-TfR, a preclinical program for the treatment of Alzheimer's disease. It has a license, development, and commercialization agreement with F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. to develop and commercialize antibodies that target a-synuclein, including prasinezumab; and master collaboration agreement with Bristol Myers Squibb to develop and commercialize antibodies targeting tau, TDP-43. Prothena Corporation plc was incorporated in 2012 and is based in Dublin, Ireland.
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| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Income before tax | - | - | -111.43M | -77.30M | -156.12M |
| Net income | - | - | -111.14M | -77.68M | -155.65M |
| Selling general administrative | - | - | 38.70M | 35.74M | 42.48M |
| Ebit | -131.56M | 71.97M | -112.73M | -85.76M | -142.71M |
| Operating income | - | - | -112.73M | -85.70M | -158.85M |
| Interest expense | - | 0.00M | 0.00M | 0.00M | 0.00M |
| Tax provision | - | - | -0.28M | 0.38M | -0.47M |
| Interest income | - | - | 1.37M | 8.20M | 2.69M |
| Income tax expense | -8.66M | 4.95M | -0.28M | 0.38M | -0.47M |
| Total revenue | - | - | 0.85M | 0.81M | 0.95M |
| Net income applicable to common shares | -116.95M | 66.97M | -111.14M | -77.68M | -155.65M |
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Total assets | - | - | 332.98M | 419.27M | 498.80M |
| Other current assets | 1.71M | 0.77M | 1.35M | - | 3.73M |
| Total liab | - | - | 148.97M | 146.35M | 175.80M |
| Total stockholder equity | - | - | 184.01M | 272.92M | 323.00M |
| Other current liab | 11.95M | 8.06M | 0.55M | 0.33M | 0.84M |
| Common stock | 0.52M | 0.47M | 0.40M | 0.40M | 0.40M |
| Retained earnings | -833.00M | -716.05M | -783.03M | -671.88M | -598.00M |
| Other liab | 85.85M | 103.49M | 110.80M | 110.80M | 110.97M |
| Other assets | 30.93M | 10.42M | 13.33M | 13.74M | 14.57M |
| Cash | - | - | 295.38M | 375.72M | 427.66M |
| Total current liabilities | 50.15M | 33.45M | 25.85M | 17.71M | 14.93M |
| Short long term debt total | - | - | - | - | 49.90M |
| Property plant equipment | 8.01M | 14.13M | 20.36M | 27.15M | 52.84M |
| Total current assets | 719.10M | 584.81M | 299.28M | 378.38M | 431.39M |
| Net tangible assets | 622.04M | 466.04M | 184.01M | 272.92M | 323.00M |
| Net receivables | 0.06M | 0.01M | 0.01M | 0.07M | 0.00M |
| Accounts payable | 9.27M | 3.69M | 4.12M | 1.24M | 1.47M |
| Breakdown | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 |
| Change to liabilities | - | - | -1.99M | -0.14M | 7.73M |
| Total cashflows from investing activities | - | - | -0.46M | -0.57M | -0.20M |
| Total cash from financing activities | - | - | 241.46M | 190.33M | 0.21M |
| Change to operating activities | - | - | -16.81M | -10.26M | -4.25M |
| Net income | -122.31M | -147.03M | -116.95M | 66.97M | -111.14M |
| Change in cash | - | - | 132.17M | 282.36M | -80.34M |
| Total cash from operating activities | - | - | -108.82M | 92.61M | -80.36M |
| Depreciation | - | - | 6.74M | 6.80M | 6.98M |
| Change to account receivables | - | - | - | 0.01M | 0.05M |
| Sale purchase of stock | - | - | - | - | 0.21M |
| Change to netincome | - | - | 20.19M | 29.23M | 20.33M |
| Capital expenditures | 0.00M | 0.00M | 0.46M | 0.57M | 0.20M |
| Change in working capital | - | - | - | - | 3.48M |
|
Stock Name
|
Change
(GBX) |
Price
(GBX) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
|---|---|---|---|---|---|---|
| 0Y3M Prothena Corp. PLC |
0.09 1.11% |
8.51 | 0.08 | - | 34.86 | - |
| 0R15 SoftBank Group Corp. |
248.00 5.84% |
4494.00 | - | - | - | - |
| 0R1E Nintendo Co. Ltd. |
-115.00 1.34% |
8476.00 | - | - | - | - |
| 0LC3 Synchrony Financial |
2.34 3.20% |
75.60 | 0.09 | - | 4.97 | - |
| 0HQP CBRE Group Inc. Cl A |
0.15 0.12% |
122.47 | 0.25 | - | 1.18 | - |
Prothena Corporation plc, a late-stage clinical biotechnology company, focuses on discovery and development of novel therapies to treat diseases caused by protein dysregulation. Its product pipeline includes Prasinezumab, an investigational humanized monoclonal antibody which is in Phase 3 clinical trial for the treatment of parkinson's disease and other synucleinopathies. The company also develops Coramitug, an investigational antibody, which is in Phase 3 clinical trial for the treatment of transthyretin amyloidosis; BMS-986446, an anti-tau antibody which is in Phase 2 clinical trial to treat Alzheimer's disease; PRX019, an investigational antibody which is in Phase 1 clinical trial for the treatment of neurodegenerative diseases; and PRX123, a Dual Aß-Tau Vaccine, which is in preclinical trial for treating Alzheimer's disease. In addition, it develops discovery- and late-preclinical-stage programs include TDP-43 CYTOPE for the treatment of amyotrophic lateral sclerosis; PRX012, a next-generation anti-Aß antibody which is in phase 1 clinical trial to treat Alzheimer's disease; and PRX012-TfR, a preclinical program for the treatment of Alzheimer's disease. It has a license, development, and commercialization agreement with F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. to develop and commercialize antibodies that target a-synuclein, including prasinezumab; and master collaboration agreement with Bristol Myers Squibb to develop and commercialize antibodies targeting tau, TDP-43. Prothena Corporation plc was incorporated in 2012 and is based in Dublin, Ireland.
| Name | Title | Year Born |
|---|---|---|
| Dr. Gene G. Kinney Ph.D. | Pres, CEO & Director | 1969 |
| Mr. Tran B. Nguyen M.B.A. | CFO & Chief Strategy Officer | 1974 |
| Mr. Brandon S. Smith | Chief Operating Officer | 1975 |
| Ms. Carol D. Karp | Chief Regulatory Officer | 1953 |
| Dr. Hideki Garren M.D., Ph.D. | Chief Medical Officer | 1965 |
| Ms. Karin L. Walker CPA, CPA | Chief Accounting Officer & Controller | 1963 |
| Dr. Wagner M. Zago | Chief Scientific Officer | 1973 |
| Ms. Jennifer Zibuda | Director of Investor Relations & Communication | NA |
| Mr. Michael J. Malecek | Chief Legal Officer | 1966 |
| Ms. Yvonne M. Tchrakian | Company Sec. | NA |
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