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BioMarin Pharmaceutical Inc., a biotechnology company, engages in the development and commercialization of therapies for life-threatening rare diseases and medical conditions in the United States, Europe, Latin America, the Middle East, the Asia Pacific, and internationally. The company's products include VIMIZIM, an enzyme replacement therapy for the treatment of mucopolysaccharidosis (MPS) IV type A, a lysosomal storage disorder; VOXZOGO, a once daily injection analog of c-type natriuretic peptide (CNP) for the treatment of achondroplasia; NAGLAZYME, a recombinant form of N- acetylgalactosamine 4-sulfatase for patients with MPS VI; and PALYNZIQ, a PEGylated recombinant phenylalanine (Phe) ammonia lyase enzyme delivered through subcutaneous injection to reduce blood Phe concentrations. It also develops BRINEURA, a recombinant human tripeptidyl peptidase 1 for the treatment of patients with ceroid lipofuscinosis type 2, a form of Batten disease; ALDURAZYME, a purified protein designed to be identical to a naturally occurring form of the human enzyme alpha-L-iduronidase; and KUVAN, a proprietary synthetic oral form of 6R-BH4 that is used to treat patients with phenylketonuria, an inherited metabolic disease. The company's products under development include BMN 333, a longer-acting CNP for the treatment of multiple growth disorders, such as achondroplasia and hypochondroplasia; and BMN 351, an oligonucleotide for the treatment of duchenne muscular dystrophy. It serves specialty pharmacies, hospitals, non-U.S. government agencies, distributors, and pharmaceutical wholesalers. The company has license and collaboration agreements with and Ares Trading S.A. The company was incorporated in 1996 and is based in San Rafael, California.
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BioMarin Pharmaceutical develops and commercializes therapies for rare genetic diseases, focusing on enzyme replacement, small-molecule, and gene therapy approaches. Its long-term growth could be driven by uptake of approved therapies, advancement of late-stage gene therapy candidates, and geographic expansion of specialty care access, which may benefit from durable demand in ultra-rare indications.
The company faces material clinical and regulatory risk from its pipeline, pricing and reimbursement pressure in specialty markets, and execution and manufacturing risks that could affect approvals and commercialization.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | 482.48M | 541.76M | 188.56M | 149.58M | -75.35M |
| Net income | 348.90M | 426.86M | 167.65M | 141.56M | -64.08M |
| Selling general administrative | 1153.02M | 532.30M | 404.00M | 403.71M | 354.30M |
| Selling and marketing expenses | 124.00M | 476.70M | 488.40M | 450.30M | 405.10M |
| Gross profit | 2484.43M | 2273.68M | 1887.16M | 1612.37M | 1375.76M |
| Reconciled depreciation | 79.56M | 96.43M | 102.08M | 101.97M | 108.04M |
| Ebit | 493.38M | 554.10M | 202.39M | 57.55M | -60.01M |
| Ebitda | 572.94M | 650.53M | 306.77M | 159.51M | 48.03M |
| Depreciation and amortization | 79.56M | 96.43M | 104.39M | 101.97M | 108.04M |
| Non operating income net other | - | - | - | - | 10.48M |
| Operating income | 533.48M | 484.21M | 185.77M | 57.55M | -60.01M |
| Other operating expenses | 2687.78M | 2369.70M | 2233.45M | 2054.48M | 1928.62M |
| Interest expense | 10.90M | 12.67M | 17.34M | 15.97M | 15.34M |
| Tax provision | 133.58M | 114.90M | 4.66M | 8.02M | -11.27M |
| Interest income | 74.90M | 74.88M | 49.01M | 18.03M | 10.48M |
| Net interest income | 64.00M | 62.15M | 34.14M | 2.06M | -4.86M |
| Income tax expense | 133.58M | 114.90M | 20.92M | 8.02M | -11.27M |
| Total revenue | 3221.25M | 2853.91M | 2419.23M | 2096.04M | 1846.28M |
| Total operating expenses | 1950.95M | 1789.47M | 1701.39M | 1570.81M | 1458.10M |
| Cost of revenue | 736.83M | 580.24M | 532.06M | 483.67M | 470.51M |
| Total other income expense net | -51.00M | 57.55M | 2.79M | 92.03M | -15.34M |
| Net income from continuing ops | 348.90M | 426.86M | 147.02M | 141.56M | -64.08M |
| Net income applicable to common shares | - | - | - | 141.56M | -64.08M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 7594.02M | 6988.94M | 6841.60M | 6375.07M | 6003.32M |
| Intangible assets | 213.84M | 255.28M | 294.70M | 338.57M | 388.65M |
| Other current assets | 185.78M | 201.53M | 141.39M | 104.52M | 110.44M |
| Total liab | 1507.02M | 1330.95M | 1890.05M | 1771.92M | 1732.59M |
| Total stockholder equity | 6087.00M | 5657.99M | 4951.55M | 4603.16M | 4270.74M |
| Other current liab | 437.58M | 334.58M | 354.24M | 346.56M | 329.40M |
| Common stock | 0.19M | 0.19M | 0.19M | 0.19M | 0.18M |
| Capital stock | 0.19M | 0.19M | 0.19M | 0.19M | 0.18M |
| Retained earnings | 154.21M | -194.69M | -621.55M | -789.20M | -925.69M |
| Other liab | - | - | - | 73.50M | 113.69M |
| Good will | 196.20M | 196.20M | 196.20M | 196.20M | 196.20M |
| Other assets | - | - | - | 1604.19M | 1600.84M |
| Cash | 1311.68M | 942.84M | 755.13M | 724.53M | 587.28M |
| Total current liabilities | 759.03M | 606.99M | 1177.02M | 588.88M | 539.82M |
| Current deferred revenue | - | 1.37M | 4.62M | 0.71M | 6.96M |
| Net debt | -668.81M | -293.38M | 378.75M | 358.49M | 491.80M |
| Short term debt | 8.69M | 23.07M | 502.66M | 10.38M | 10.46M |
| Short long term debt | - | - | 493.88M | - | - |
| Short long term debt total | 642.87M | 649.47M | 1133.88M | 1083.02M | 1079.08M |
| Other stockholder equity | 5956.58M | 5790.84M | 5611.56M | 5396.04M | 5181.81M |
| Property plant equipment | - | - | - | 1114.32M | 1035.46M |
| Total current assets | 3953.49M | 3232.43M | 2956.09M | 2751.46M | 2274.39M |
| Long term investments | 492.24M | 521.24M | 611.13M | 333.83M | 507.79M |
| Net tangible assets | - | - | - | 4068.39M | 3685.89M |
| Short term investments | 248.93M | 194.86M | 318.68M | 567.01M | 426.60M |
| Net receivables | 908.21M | 660.53M | 633.70M | 461.32M | 373.40M |
| Long term debt | 597.18M | 595.14M | 593.10M | 1083.02M | 1079.08M |
| Inventory | 1298.88M | 1232.65M | 1107.18M | 894.08M | 776.67M |
| Accounts payable | 312.77M | 235.40M | 315.51M | 231.24M | 193.00M |
| Accumulated other comprehensive income | -23.98M | 61.65M | -38.65M | -3.87M | 14.43M |
| Common stock total equity | - | - | - | - | 0.18M |
| Retained earnings total equity | - | - | - | - | -925.69M |
| Non currrent assets other | 277.05M | 251.39M | 121.22M | 176.24M | 151.76M |
| Non current assets total | 3640.53M | 3756.51M | 3885.51M | 3623.62M | 3728.94M |
| Capital lease obligations | 8.69M | 7.57M | 8.78M | 10.38M | 10.46M |
| Long term debt total | - | - | - | - | 1079.08M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | -18.07M | 136.49M | -100.99M | -20.03M | -366.31M |
| Change to liabilities | - | - | - | 59.02M | 12.35M |
| Total cashflows from investing activities | -414.24M | 136.49M | -111.24M | -20.03M | -366.31M |
| Net borrowings | 0.00M | -494.99M | 0.00M | -2.60M | -3.04M |
| Total cash from financing activities | -42.39M | -526.45M | -18.73M | -18.65M | -0.05M |
| Change to operating activities | - | - | - | -5.10M | 19.83M |
| Net income | 348.90M | 426.86M | 167.65M | 141.56M | -64.08M |
| Change in cash | 368.84M | 187.72M | 30.60M | 137.25M | -61.88M |
| Begin period cash flow | 942.84M | 755.13M | 724.53M | 587.28M | 649.16M |
| End period cash flow | 1311.68M | 942.84M | 755.13M | 724.53M | 587.28M |
| Total cash from operating activities | 827.99M | 572.84M | 159.26M | 175.90M | 304.54M |
| Depreciation | 79.56M | 96.43M | 104.39M | 101.97M | 108.04M |
| Other cashflows from investing activities | -7.94M | -0.85M | -10.92M | 103.33M | -24.64M |
| Change to inventory | 119.21M | -63.53M | -157.06M | -68.26M | -35.06M |
| Change to account receivables | -228.05M | -57.91M | -190.44M | -82.03M | 65.57M |
| Sale purchase of stock | - | -77.56M | -76.32M | 0.00M | 49.19M |
| Other cashflows from financing activities | -42.39M | -31.46M | -85.79M | -16.05M | 2.99M |
| Change to netincome | - | - | - | 28.75M | 185.24M |
| Capital expenditures | 103.04M | 97.42M | 96.69M | 131.54M | 119.22M |
| Change receivables | - | - | - | - | 65.57M |
| Cash flows other operating | - | - | - | - | 23.17M |
| Exchange rate changes | - | - | - | - | -0.06M |
| Cash and cash equivalents changes | - | - | - | - | -61.88M |
| Change in working capital | -108.68M | -216.40M | -336.54M | -96.38M | 66.03M |
| Stock based compensation | 181.41M | 201.57M | 207.10M | 196.31M | 197.26M |
| Other non cash items | 278.07M | 8.29M | 61.65M | -115.47M | 12.89M |
| Free cash flow | 724.96M | 475.42M | 62.57M | 44.36M | 185.31M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| BMRN Biomarin Pharmaceutical Inc |
-1.60 2.79% |
55.84 | 30.51 | 10.81 | 3.26 | 1.73 | 2.96 | 16.67 |
| NVO Novo Nordisk A/S |
-0.24 0.61% |
40.20 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
-21.28 3.85% |
531.87 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
12.10 1.26% |
973.36 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
BioMarin Pharmaceutical Inc., a biotechnology company, engages in the development and commercialization of therapies for life-threatening rare diseases and medical conditions in the United States, Europe, Latin America, the Middle East, the Asia Pacific, and internationally. The company's products include VIMIZIM, an enzyme replacement therapy for the treatment of mucopolysaccharidosis (MPS) IV type A, a lysosomal storage disorder; VOXZOGO, a once daily injection analog of c-type natriuretic peptide (CNP) for the treatment of achondroplasia; NAGLAZYME, a recombinant form of N- acetylgalactosamine 4-sulfatase for patients with MPS VI; and PALYNZIQ, a PEGylated recombinant phenylalanine (Phe) ammonia lyase enzyme delivered through subcutaneous injection to reduce blood Phe concentrations. It also develops BRINEURA, a recombinant human tripeptidyl peptidase 1 for the treatment of patients with ceroid lipofuscinosis type 2, a form of Batten disease; ALDURAZYME, a purified protein designed to be identical to a naturally occurring form of the human enzyme alpha-L-iduronidase; and KUVAN, a proprietary synthetic oral form of 6R-BH4 that is used to treat patients with phenylketonuria, an inherited metabolic disease. The company's products under development include BMN 333, a longer-acting CNP for the treatment of multiple growth disorders, such as achondroplasia and hypochondroplasia; and BMN 351, an oligonucleotide for the treatment of duchenne muscular dystrophy. It serves specialty pharmacies, hospitals, non-U.S. government agencies, distributors, and pharmaceutical wholesalers. The company has license and collaboration agreements with and Ares Trading S.A. The company was incorporated in 1996 and is based in San Rafael, California.
| Name | Title | Year Born |
|---|---|---|
| Mr. Jean-Jacques Bienaime M.B.A., MBA | Chairman & CEO | 1953 |
| Mr. Brian R. Mueller | Exec. VP of Fin. & CFO | 1974 |
| Dr. C. Greg Guyer Ph.D. | CTO and Exec. VP of Global Manufacturing & Technical Operations | 1962 |
| Mr. Jeffrey Robert Ajer | Exec. VP & Chief Commercial Officer | 1962 |
| Dr. Henry J. Fuchs M.D., Ph.D. | Pres of Worldwide R&D | 1958 |
| Ms. Erin Burkhart | Group VP & Chief Accounting Officer | NA |
| Traci McCarty | VP of Investor Relations | NA |
| Mr. George Eric Davis | Exec. VP, Gen. Counsel & Sec. | 1971 |
| Mr. Philip Lo Scalzo | Sr. VP & Chief Compliance Officer | NA |
| Ms. Humaira Serajuddin | Sr. VP & Chief Marketing Officer | NA |
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