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Dyne Therapeutics, Inc., a clinical-stage neuromuscular disease company, focuses on discovering and developing therapeutics for neuromuscular diseases in the United States. It is developing a portfolio of muscle disease therapeutics, including programs in myotonic dystrophy type 1; duchenne muscular dystrophy; facioscapulohumeral dystrophy; and Pompe disease, as well as rare skeletal muscle, and cardiac and metabolic muscle diseases using its FORCE platform that delivers disease-modifying therapeutics. The company was incorporated in 2017 and is headquartered in Waltham, Massachusetts.
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Dyne Therapeutics is a clinical-stage biotechnology company developing targeted genetic medicines for rare neuromuscular diseases using a proprietary delivery platform intended to improve tissue targeting of oligonucleotide therapeutics. Long-term growth drivers include advancement of its pipeline through clinical trials, potential regulatory approvals and commercialization, and platform expansion or partnering that could broaden addressable indications and may appeal to investors seeking exposure to delivery-focused genetic therapies. Investors should monitor development milestones and financing needs.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Income before tax | -168.10M | -149.29M | -59.44M | -14.86M | -4.81M |
| Net income | -165.24M | -149.28M | -58.74M | -13.54M | -4.81M |
| Selling general administrative | 28.20M | 28.72M | 13.45M | 2.79M | 0.52M |
| Reconciled depreciation | 1.68M | 1.09M | 0.70M | 0.27M | 0.02M |
| Ebit | -172.65M | -150.03M | -59.35M | -13.83M | -4.81M |
| Ebitda | -170.96M | -148.20M | -58.65M | -14.59M | -4.79M |
| Depreciation and amortization | 1.68M | 1.82M | 0.70M | -0.76M | 0.02M |
| Operating income | -170.96M | -150.03M | -58.65M | -13.83M | -4.79M |
| Other operating expenses | 170.96M | 150.03M | 58.65M | 13.83M | 4.79M |
| Interest expense | 2.92M | 0.74M | 0.40M | 0.29M | 0.01M |
| Interest income | 2.92M | 0.74M | 0.06M | 0.29M | 0.01M |
| Net interest income | 2.92M | 0.74M | -0.34M | 0.29M | 0.01M |
| Income tax expense | -2.86M | -0.01M | -0.70M | -1.32M | -0.01M |
| Total revenue | 0.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Total operating expenses | 170.96M | 150.03M | 58.65M | 13.83M | 4.79M |
| Total other income expense net | 2.86M | 0.73M | -0.79M | -1.03M | -0.02M |
| Net income from continuing ops | -168.10M | -149.29M | -59.44M | -14.86M | -4.81M |
| Net income applicable to common shares | -168.10M | -149.29M | -59.44M | -14.86M | -4.81M |
| Breakdown | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 |
| Total assets | 691.23M | 165.08M | 306.32M | 425.66M | 353.33M |
| Other current assets | 17.01M | 6.28M | 9.58M | 5.82M | 3.77M |
| Total liab | 61.40M | 73.79M | 53.96M | 57.47M | 10.97M |
| Total stockholder equity | 629.84M | 91.29M | 252.36M | 368.20M | 342.37M |
| Other current liab | 30.85M | 23.44M | 18.22M | 20.80M | 7.53M |
| Common stock | 0.01M | 0.01M | 0.01M | 0.01M | 0.01M |
| Capital stock | 0.01M | 0.01M | 0.01M | 0.01M | 0.01M |
| Retained earnings | -949.93M | -632.51M | -396.57M | -228.47M | -79.18M |
| Other assets | - | 0.00M | 2.32M | 2.31M | 2.30M |
| Cash | 435.45M | 121.63M | 172.15M | 200.82M | 300.85M |
| Total current liabilities | 42.26M | 51.09M | 28.09M | 28.72M | 10.97M |
| Net debt | -411.46M | -94.21M | -141.66M | -168.19M | -300.85M |
| Short term debt | 4.85M | 4.72M | 4.61M | 3.89M | - |
| Short long term debt total | 23.99M | 27.41M | 30.48M | 32.64M | - |
| Other stockholder equity | 1579.75M | 723.80M | 649.50M | 596.93M | 421.57M |
| Property plant equipment | - | - | 38.41M | 40.96M | 1.95M |
| Total current assets | 659.28M | 129.38M | 256.01M | 382.39M | 345.31M |
| Net tangible assets | - | - | 252.36M | 368.20M | 342.37M |
| Short term investments | 206.82M | 1.47M | 83.86M | 175.75M | 44.46M |
| Accounts payable | 6.56M | 22.94M | 5.26M | 4.03M | 3.44M |
| Accumulated other comprehensive income | 0.01M | - | -0.57M | -0.27M | -0.03M |
| Common stock total equity | - | - | - | - | 0.01M |
| Non currrent assets other | 1.94M | -0.00M | 11.90M | 2.31M | 6.07M |
| Non current assets total | 31.95M | 35.71M | 50.31M | 43.27M | 8.02M |
| Capital lease obligations | 23.99M | 27.41M | 30.48M | 32.64M | - |
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Investments | 87.20M | -134.27M | -45.66M | -1.65M | -0.13M |
| Change to liabilities | -1.24M | 13.70M | 8.57M | 1.69M | 0.64M |
| Total cashflows from investing activities | 87.20M | -137.89M | -45.66M | -1.65M | -0.13M |
| Net borrowings | - | - | -0.06M | -0.06M | -0.06M |
| Total cash from financing activities | 37.39M | 157.82M | 380.69M | 19.99M | 12.42M |
| Change to operating activities | -4.14M | -4.45M | -3.46M | -0.28M | -0.03M |
| Net income | -168.10M | -149.29M | -59.44M | -14.86M | -4.81M |
| Change in cash | -29.05M | -99.63M | 288.52M | 6.51M | 12.42M |
| Begin period cash flow | 203.52M | 303.15M | 14.63M | 8.12M | -4.30M |
| End period cash flow | 174.47M | 203.52M | 303.15M | 14.63M | 8.12M |
| Total cash from operating activities | -153.65M | -119.56M | -46.51M | -11.83M | -4.16M |
| Issuance of capital stock | 36.86M | 157.24M | 381.17M | 19.99M | 7.42M |
| Depreciation | 1.68M | 1.09M | 0.70M | 0.27M | 0.02M |
| Sale purchase of stock | - | - | - | 19.99M | 7.42M |
| Other cashflows from financing activities | 0.53M | 0.58M | 144.30M | -1.65M | 12.41M |
| Change to netincome | 18.15M | 19.38M | 7.05M | 1.35M | 0.02M |
| Capital expenditures | 3.07M | 3.62M | 1.16M | 1.65M | 0.13M |
| Change in working capital | -5.38M | 9.26M | 5.11M | 1.41M | 0.60M |
| Stock based compensation | 15.18M | 17.54M | 6.59M | 0.03M | 0.00M |
| Other non cash items | 2.97M | -0.75M | 0.51M | 1.32M | 0.02M |
| Free cash flow | -156.71M | -123.18M | -47.67M | -13.48M | -4.30M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|
| DYN Dyne Therapeutics Inc |
0.07 0.39% |
17.99 | - | - | - | 2.01 | -8.87 |
| NVO Novo Nordisk A/S |
0.41 1.00% |
41.10 | 41.58 | 31.15 | 2.13 | 32.99 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
-2.37 0.43% |
544.66 | 30.22 | 24.27 | 10.36 | 6.50 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
43.35 4.73% |
959.41 | 29.07 | 20.12 | 7.57 | 3.82 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 36.06 |
Dyne Therapeutics, Inc., a clinical-stage neuromuscular disease company, focuses on discovering and developing therapeutics for neuromuscular diseases in the United States. It is developing a portfolio of muscle disease therapeutics, including programs in myotonic dystrophy type 1; duchenne muscular dystrophy; facioscapulohumeral dystrophy; and Pompe disease, as well as rare skeletal muscle, and cardiac and metabolic muscle diseases using its FORCE platform that delivers disease-modifying therapeutics. The company was incorporated in 2017 and is headquartered in Waltham, Massachusetts.
| Name | Title | Year Born |
|---|---|---|
| Mr. Joshua T. Brumm | CEO, Pres & Director | 1978 |
| Ms. Susanna Gatti High M.B.A. | Chief Operating Officer | 1968 |
| Dr. Oxana Beskrovnaya Ph.D. | Chief Scientific Officer | 1961 |
| Dr. Romesh Subramanian Ph.D. | Co-Founder & Advisor | 1965 |
| Mr. Gene Kim | VP of Fin. | 1977 |
| Mr. Richard William Scalzo M.B.A. | Sr. VP, Head of Fin. & Admin. and Treasurer | 1986 |
| Ms. Amy Reilly | Sr. VP and Head of Corp. Communications & Investor Relations | 1974 |
| Ms. Kate Mitchell | VP & Head of HR | NA |
| Dr. Thomas-Christian Mix M.D., M.S. | Sr. VP of Pharmacovigilance | 1967 |
| Ms. Debra Feldman | Sr. VP & Head of Regulatory Affairs | 1970 |
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