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NRx Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, develops therapeutics for the treatment of central nervous system disorders comprising suicidal depression, post-traumatic stress disorder (PTSD), and schizophrenia in the United States. It operates through NRx and Dura segments. The company develops NRX-101, an oral fixed-dose combination of D-cycloserine (DCS) and lurasidone in Phase 2/3 clinical testing for bipolar depression with sub-acute ideation and behavior; NRX-100, a preservative-free formulation of ketamine for intravenous infusion and for the treatment of suicidal depression; and KETAFREE, a generic preservative-free formulation of ketamine. It also provides precision-based interventional psychiatry services to patients with treatment-resistant depression and PTSD using a combination of neuroplastic drugs, transcranial magnetic stimulation (TMS), digital therapeutics, and hyperbaric therapy; ketamine infusion therapy; stellate ganglion blocks; Spravato administration; psychotherapy; and medication management. The company has a development and license agreement with Glytech LLC. NRx Pharmaceuticals, Inc. was founded in 2015 and is headquartered in Wilmington, Delaware.
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| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | -28.62M | -25.13M | -30.15M | -39.82M | -93.06M |
| Net income | -28.62M | -25.13M | -30.15M | -35.23M | -71.72M |
| Selling general administrative | 13.06M | 13.51M | 14.22M | 27.37M | 74.94M |
| Selling and marketing expenses | - | - | 0.01M | - | - |
| Gross profit | 0.72M | -0.01M | -0.01M | - | - |
| Reconciled depreciation | 0.14M | 0.01M | 0.01M | 0.00M | 0.00M |
| Ebit | -27.95M | -24.05M | -30.03M | -44.40M | -115.80M |
| Ebitda | -27.81M | -24.04M | -30.02M | -44.65M | -115.79M |
| Depreciation and amortization | 0.14M | 0.01M | 0.01M | -0.26M | 0.00M |
| Operating income | -16.22M | -19.70M | -27.59M | -44.40M | -115.80M |
| Other operating expenses | 17.45M | 19.70M | 27.59M | 44.40M | 94.43M |
| Interest expense | 0.67M | 1.08M | 0.12M | -4.58M | 0.02M |
| Tax provision | - | - | - | 0.00M | 0.00M |
| Interest income | 0.01M | 0.04M | 0.55M | 0.25M | - |
| Net interest income | -0.66M | -0.19M | 0.51M | 0.25M | -0.02M |
| Income tax expense | - | - | -0.01M | -4.58M | -21.35M |
| Total revenue | 1.23M | 0.00M | 0.00M | 0.00M | 0.00M |
| Total operating expenses | 16.94M | 19.70M | 27.58M | 44.40M | 94.43M |
| Cost of revenue | 0.51M | 0.01M | 0.01M | - | - |
| Total other income expense net | -12.40M | -5.42M | -2.56M | 4.58M | 22.73M |
| Net income from continuing ops | -28.62M | -25.13M | -36.06M | -39.75M | -93.06M |
| Net income applicable to common shares | - | - | - | -39.75M | -348.88M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 12.96M | 3.65M | 7.32M | 25.82M | 32.73M |
| Intangible assets | 0.93M | - | - | - | - |
| Other current assets | 0.93M | 1.86M | 2.29M | 5.74M | 5.11M |
| Total liab | 28.89M | 26.87M | 19.05M | 18.41M | 11.92M |
| Total stockholder equity | -15.94M | -23.22M | -11.73M | 7.41M | 20.81M |
| Other current liab | 23.99M | 16.17M | 5.25M | 5.81M | 4.87M |
| Common stock | 0.03M | 0.01M | 0.08M | 0.07M | 0.06M |
| Capital stock | 0.03M | 0.01M | 0.09M | 0.07M | 0.06M |
| Retained earnings | -306.89M | -278.27M | -253.15M | -223.06M | -183.24M |
| Good will | 1.79M | 0.00M | - | - | - |
| Other assets | - | - | - | - | 0.01M |
| Cash | 7.80M | 1.44M | 4.59M | 20.05M | 27.61M |
| Total current liabilities | 28.58M | 21.86M | 19.05M | 16.59M | 11.92M |
| Current deferred revenue | - | - | - | - | 2.84M |
| Net debt | -7.17M | 5.13M | 4.57M | -9.53M | -27.09M |
| Short term debt | 0.32M | 1.57M | 9.16M | 8.70M | 0.52M |
| Short long term debt | - | 1.57M | 9.16M | 7.70M | 0.52M |
| Short long term debt total | 0.63M | 6.58M | 9.16M | 10.53M | 0.52M |
| Other stockholder equity | 290.93M | 255.03M | 241.33M | 230.40M | 203.99M |
| Total current assets | 8.89M | 3.30M | 6.88M | 25.80M | 32.71M |
| Long term investments | 0.40M | 0.00M | - | - | - |
| Net tangible assets | - | - | - | 7.41M | 20.81M |
| Net receivables | 0.16M | 0.00M | 0.01M | 0.01M | 0.00M |
| Long term debt | - | 5.01M | - | 2.82M | - |
| Inventory | - | - | -0.01M | -0.01M | - |
| Accounts payable | 4.27M | 4.13M | 4.63M | 2.08M | 3.69M |
| Accumulated other comprehensive income | - | - | -0.00M | - | - |
| Non currrent assets other | 0.32M | 0.35M | 0.43M | 0.02M | 0.01M |
| Non current assets total | 4.06M | 0.35M | 0.43M | 0.02M | 0.01M |
| Capital lease obligations | 0.63M | 0.00M | - | - | - |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | -0.43M | 0.00M | -0.00M | -0.01M | -0.01M |
| Change to liabilities | - | - | - | 0.00M | -0.02M |
| Total cashflows from investing activities | -2.81M | - | -0.00M | -0.01M | -0.01M |
| Net borrowings | 4.68M | -1.50M | -3.09M | - | -1.28M |
| Total cash from financing activities | 23.28M | 7.49M | 6.20M | 32.21M | 63.46M |
| Change to operating activities | - | - | - | 2.31M | -5.71M |
| Net income | -28.62M | -25.13M | -30.15M | -39.75M | -93.06M |
| Change in cash | 6.35M | -3.15M | -15.46M | -7.55M | 25.75M |
| Begin period cash flow | 1.44M | 4.59M | 20.05M | 27.61M | 1.86M |
| End period cash flow | 7.80M | 1.44M | 4.59M | 20.05M | 27.61M |
| Total cash from operating activities | -14.11M | -10.64M | -21.66M | -39.76M | -37.70M |
| Issuance of capital stock | 15.86M | 5.91M | 9.38M | 22.70M | 36.98M |
| Depreciation | 0.14M | 0.01M | 0.01M | 0.00M | 0.00M |
| Other cashflows from investing activities | -0.43M | - | - | - | - |
| Change to account receivables | 0.05M | 0.00M | - | 0.00M | 0.83M |
| Other cashflows from financing activities | -0.35M | 3.07M | 1.17M | 10.03M | 27.75M |
| Change to netincome | - | - | - | - | 60.26M |
| Capital expenditures | 0.00M | 0.00M | 0.00M | 0.01M | 0.01M |
| Change in working capital | 1.41M | 5.29M | 5.16M | 0.70M | -4.90M |
| Stock based compensation | 0.23M | 0.49M | 0.39M | 3.63M | 7.79M |
| Other non cash items | 12.73M | 8.71M | 2.94M | -4.33M | 54.28M |
| Free cash flow | -14.11M | -10.64M | -21.66M | -39.77M | -37.71M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| NRXP NRX Pharmaceuticals Inc |
-0.14 5.74% |
2.30 | - | 34.25 | 43.37 | 2.90 | 37.15 | -0.15 |
| NVO Novo Nordisk A/S |
-0.54 1.32% |
40.55 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
-2.37 0.43% |
544.66 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
-2.77 0.29% |
956.64 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
NRx Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, develops therapeutics for the treatment of central nervous system disorders comprising suicidal depression, post-traumatic stress disorder (PTSD), and schizophrenia in the United States. It operates through NRx and Dura segments. The company develops NRX-101, an oral fixed-dose combination of D-cycloserine (DCS) and lurasidone in Phase 2/3 clinical testing for bipolar depression with sub-acute ideation and behavior; NRX-100, a preservative-free formulation of ketamine for intravenous infusion and for the treatment of suicidal depression; and KETAFREE, a generic preservative-free formulation of ketamine. It also provides precision-based interventional psychiatry services to patients with treatment-resistant depression and PTSD using a combination of neuroplastic drugs, transcranial magnetic stimulation (TMS), digital therapeutics, and hyperbaric therapy; ketamine infusion therapy; stellate ganglion blocks; Spravato administration; psychotherapy; and medication management. The company has a development and license agreement with Glytech LLC. NRx Pharmaceuticals, Inc. was founded in 2015 and is headquartered in Wilmington, Delaware.
1201 N. Market Street, Wilmington, DE, United States, 19801
484 254 6134
29
| Name | Title | Year Born |
|---|---|---|
| Dr. Jonathan C. Javitt M.D., M.P.H. | Co-Founder, Chief Scientist & Director | 1957 |
| Mr. Robert Besthof M.I.M. | Head of Operations, Chief Commercial & Patient Officer | 1966 |
| Mr. Stephen H. Willard Esq. | CEO & Director | 1961 |
| Prof. Daniel C. Javitt | Co-Founder & Chairman of Scientific Advisory Board | NA |
| Dr. Seth L. Van Voorhees Ph.D. | CFO & Treasurer | 1961 |
| Suzanne Messere | Investor Relations | NA |
| Dr. Michael Kunz | Gen. Counsel & Corp. Sec. | 1965 |
| Ms. Molly Cogan | Sr. Director of Global Communications & Gov. Affairs | NA |
| Dr. Philip T. Lavin Ph.D. | Chief Methodologist | 1947 |
| Dr. Dennis K. McBride Ph.D. | Chief Strategy Officer & Sr. Scientist | NA |
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