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Sana Biotechnology, Inc., a biotechnology company, focuses on utilizing engineered cells as medicines in the United States. It develops ex vivo and in vivo cell engineering platforms for various therapeutic areas with unmet treatment needs, including type 1 diabetes, B cell mediated autoimmune diseases, and oncology. The company's product pipeline includes UP421, a HIP-modified allogeneic primary islet cell product, which is in phase 1 clinical trial to treat type 1 diabetes; SC451, a HIP-modified, stem cell derived pancreatic islet cell therapy, which is in preclinical trial for the treatment of type 1 diabetes; SG293 and SG299, a CD8-targeted fusosome for the treatment of B cell hematologic malignancies and B cell mediated autoimmune diseases. The company has an option and license agreement with Beam Therapeutics Inc. for use of Beam's proprietary CRISPR Cas12b nuclease editing technology to research, develop, and commercialize engineered cell therapy products; and a license agreement with Harvard College to access certain intellectual property for the development of hypoimmune-modified cells. The company has a strategic collaboration with Mayo Clinic for the development of SC451, a hypoimmune-modified pancreatic islet cell therapy for type 1 diabetes. The company was formerly known as FD Therapeutics, Inc. and changed its name to Sana Biotechnology, Inc. in September 2018. Sana Biotechnology, Inc. was incorporated in 2018 and is headquartered in Seattle, Washington.
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| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | -244.17M | -266.76M | -283.25M | -269.48M | -355.93M |
| Net income | -244.17M | -266.76M | -283.25M | -266.39M | -344.18M |
| Selling general administrative | 44.30M | 64.04M | 73.30M | 71.56M | 50.41M |
| Selling and marketing expenses | - | - | 73.23M | - | - |
| Gross profit | -12.75M | -15.49M | -30.86M | - | - |
| Reconciled depreciation | 12.75M | 17.39M | 24.56M | 15.62M | 11.07M |
| Ebit | -244.17M | -266.76M | -283.25M | -288.19M | -367.98M |
| Ebitda | -231.42M | -249.37M | -258.70M | -272.56M | -356.91M |
| Depreciation and amortization | 12.75M | 17.39M | 24.56M | 15.62M | 11.07M |
| Non operating income net other | - | - | - | -0.67M | 0.30M |
| Operating income | -190.96M | -272.72M | -293.14M | -272.56M | -356.91M |
| Other operating expenses | 190.96M | 272.72M | 293.14M | 272.56M | 356.91M |
| Interest expense | - | - | - | -15.62M | 11.07M |
| Tax provision | - | - | - | - | 0.00M |
| Interest income | 3.85M | 10.47M | 9.94M | 3.76M | 0.68M |
| Net interest income | 3.85M | 10.47M | 9.94M | 3.76M | 0.68M |
| Income tax expense | - | - | - | -3.09M | -11.75M |
| Total revenue | 0.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Total operating expenses | 178.21M | 272.72M | 293.14M | 272.56M | 356.91M |
| Cost of revenue | 12.75M | 15.49M | 30.86M | - | - |
| Total other income expense net | -53.21M | 5.96M | 9.89M | 3.09M | 0.98M |
| Net income from continuing ops | -244.17M | -266.76M | -283.25M | -269.48M | -355.93M |
| Net income applicable to common shares | - | - | - | -269.48M | -355.93M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 416.89M | 501.02M | 565.30M | 822.72M | 1129.41M |
| Intangible assets | 59.20M | 59.20M | 59.20M | 59.20M | 59.20M |
| Other current assets | 10.29M | 8.31M | 4.49M | 14.37M | 7.11M |
| Total liab | 256.01M | 250.52M | 277.79M | 323.40M | 400.90M |
| Total stockholder equity | 160.88M | 250.50M | 287.51M | 499.31M | 728.50M |
| Other current liab | 62.12M | 27.69M | 47.18M | 96.25M | 56.38M |
| Common stock | 0.03M | 0.02M | 0.02M | 0.02M | 0.02M |
| Capital stock | 0.03M | 0.02M | 0.02M | 0.02M | 0.02M |
| Retained earnings | -1849.02M | -1604.85M | -1338.09M | -1054.84M | -785.36M |
| Other liab | - | - | - | 116.04M | 199.89M |
| Good will | 140.63M | 140.63M | 140.63M | 140.63M | 140.63M |
| Other assets | - | - | - | 9.01M | 13.82M |
| Cash | 71.87M | 127.57M | 137.35M | 176.76M | 253.03M |
| Total current liabilities | 78.73M | 45.43M | 64.49M | 111.50M | 99.23M |
| Current deferred revenue | - | - | - | - | 31.48M |
| Net debt | 6.99M | -33.37M | -33.25M | -68.51M | -142.09M |
| Short term debt | 14.94M | 12.53M | 13.20M | 12.39M | 9.16M |
| Short long term debt total | 78.86M | 94.20M | 104.10M | 108.25M | 110.94M |
| Other stockholder equity | 2009.85M | 1855.32M | 1625.64M | 1558.46M | 385.80M |
| Property plant equipment | - | - | - | 66.92M | 65.46M |
| Total current assets | 148.68M | 160.81M | 213.51M | 444.44M | 558.10M |
| Long term investments | - | - | 0.00M | 10.05M | 195.88M |
| Net tangible assets | - | - | - | 299.49M | 528.68M |
| Short term investments | 66.51M | 24.93M | 71.68M | 247.20M | 297.97M |
| Accounts payable | 1.67M | 5.21M | 4.11M | 2.86M | 2.22M |
| Accumulated other comprehensive income | 0.03M | 0.01M | -0.06M | -4.33M | -1.37M |
| Common stock total equity | - | - | - | 0.02M | 0.02M |
| Retained earnings total equity | - | - | - | -1054.84M | -785.36M |
| Non currrent assets other | 3.17M | 5.12M | 6.37M | 9.01M | 13.82M |
| Non current assets total | 268.21M | 340.21M | 351.78M | 378.28M | 571.31M |
| Capital lease obligations | 78.86M | 94.20M | 104.10M | 108.25M | 110.94M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | -40.73M | 17.45M | 172.01M | 231.44M | -211.36M |
| Change to liabilities | - | - | - | 11.97M | 5.57M |
| Total cashflows from investing activities | -40.24M | 17.45M | 172.01M | 210.56M | -245.80M |
| Net borrowings | 126.06M | 7.74M | 27.02M | - | - |
| Total cash from financing activities | 128.73M | 199.75M | 31.65M | 4.91M | 631.75M |
| Change to operating activities | - | - | - | 6.48M | 10.07M |
| Net income | -244.17M | -266.76M | -283.25M | -269.48M | -355.93M |
| Change in cash | -55.33M | -5.95M | -49.92M | -74.58M | 134.90M |
| Begin period cash flow | 131.40M | 137.35M | 187.27M | 261.85M | 126.95M |
| End period cash flow | 76.06M | 131.40M | 137.35M | 187.27M | 261.85M |
| Total cash from operating activities | -143.83M | -223.15M | -253.58M | -290.05M | -251.05M |
| Issuance of capital stock | - | 181.00M | 31.65M | 0.60M | 626.40M |
| Depreciation | 12.75M | 15.50M | 24.56M | 15.62M | 11.07M |
| Other cashflows from investing activities | 1.43M | 17.45M | 0.19M | - | -4.57M |
| Sale purchase of stock | - | - | - | 0.60M | 626.40M |
| Other cashflows from financing activities | 128.73M | -181.00M | 172.01M | 4.31M | 5.35M |
| Change to netincome | - | - | - | 25.67M | 51.13M |
| Capital expenditures | 0.94M | 33.43M | 20.03M | 20.88M | 29.86M |
| Cash flows other operating | - | - | - | -73.84M | 37.10M |
| Cash and cash equivalents changes | - | - | - | -74.58M | 134.90M |
| Change in working capital | -10.11M | -1.19M | 18.61M | 7.54M | 9.80M |
| Stock based compensation | 25.46M | 37.68M | 35.53M | 38.34M | 22.36M |
| Other non cash items | 72.24M | -8.39M | -49.03M | -82.08M | 61.64M |
| Free cash flow | -144.77M | -256.58M | -273.61M | -310.93M | -280.92M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|
| SANA Sana Biotechnology Inc |
-0.14 6.33% |
2.15 | - | - | - | 6.20 | -1.08 |
| NVO Novo Nordisk A/S |
-0.54 1.32% |
40.55 | 41.58 | 31.15 | 2.13 | 32.99 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
-2.37 0.43% |
544.66 | 30.22 | 24.27 | 10.36 | 6.50 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
-2.77 0.29% |
956.64 | 29.07 | 20.12 | 7.57 | 3.82 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 36.06 |
Sana Biotechnology, Inc., a biotechnology company, focuses on utilizing engineered cells as medicines in the United States. It develops ex vivo and in vivo cell engineering platforms for various therapeutic areas with unmet treatment needs, including type 1 diabetes, B cell mediated autoimmune diseases, and oncology. The company's product pipeline includes UP421, a HIP-modified allogeneic primary islet cell product, which is in phase 1 clinical trial to treat type 1 diabetes; SC451, a HIP-modified, stem cell derived pancreatic islet cell therapy, which is in preclinical trial for the treatment of type 1 diabetes; SG293 and SG299, a CD8-targeted fusosome for the treatment of B cell hematologic malignancies and B cell mediated autoimmune diseases. The company has an option and license agreement with Beam Therapeutics Inc. for use of Beam's proprietary CRISPR Cas12b nuclease editing technology to research, develop, and commercialize engineered cell therapy products; and a license agreement with Harvard College to access certain intellectual property for the development of hypoimmune-modified cells. The company has a strategic collaboration with Mayo Clinic for the development of SC451, a hypoimmune-modified pancreatic islet cell therapy for type 1 diabetes. The company was formerly known as FD Therapeutics, Inc. and changed its name to Sana Biotechnology, Inc. in September 2018. Sana Biotechnology, Inc. was incorporated in 2018 and is headquartered in Seattle, Washington.
| Name | Title | Year Born |
|---|---|---|
| Dr. Steven D. Harr M.D. | Pres, CEO & Director | 1970 |
| Dr. Richard C. Mulligan Ph.D. | Exec. Vice Chairman & Head of SanaX | 1955 |
| Mr. Nathan Hardy M.B.A. | Exec. VP & CFO | 1976 |
| Dr. Sunil Agarwal M.D. | Exec. VP, Head of Devel. & Chief Medical Officer | 1970 |
| Ms. Shanna Clouse Peek | Sr. VP & Head of Corp. Operations | NA |
| Brittany Mccleery | Accounting Mang. | NA |
| Dr. Edward Rebar Ph.D. | Sr. VP & CTO | 1968 |
| Mr. Bernard J. Cassidy J.D. | Exec. VP & Gen. Counsel | 1955 |
| Ms. Robin Andrulevich | Exec. VP & Chief People Officer | 1966 |
| Mr. Paul Brunetta M.D. | Sr. VP and Head of Clinical & Translational Science | NA |
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