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Zentalis Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on discovering and developing small molecule therapeutics for the treatment of various cancers in the United States. It develops azenosertib, which is in a Phase 3 clinical trial for the treatment of ovarian cancer and other tumor types. The company also develops ZN-c3-001, a phase 1 study that evaluated azenosertib monotherapy in solid tumors; and MAMMOTH (ZN-c3-006) is a Phase 1/2 clinical trial of azenosertib in patients with PARP-inhibitor resistant ovarian cancer. It has licensing agreements and strategic collaborations with Recurium IP Holdings, LLC. Zentalis Pharmaceuticals, Inc. was incorporated in 2014 and is based in San Diego, California.
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A unique technical analysis driven score developed by Kalkine showing momentum in stock prices based on select technical indicators identified.
Zentalis Pharmaceuticals LLC is a clinical-stage biopharmaceutical company developing small-molecule oncology therapies across a pipeline of targeted candidates. Long-term growth drivers include advancement of clinical programs, regulatory approvals, and potential strategic partnerships that could support commercialization. Investors may find upside in positive trial readouts and a targeted pipeline addressing multiple cancer indications.
Main risks are high clinical and regulatory failure probability, absence of product revenue and recurring financing needs, and competition from larger oncology companies.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | -136.62M | -165.69M | -292.91M | -221.30M | -164.56M |
| Minority interest | 0.00M | 0.03M | 0.10M | -0.31M | -7.37M |
| Net income | -137.06M | -165.84M | -292.19M | -220.83M | -164.26M |
| Selling general administrative | 37.72M | 87.11M | 59.40M | 54.55M | 40.94M |
| Selling and marketing expenses | - | - | 1.39M | - | - |
| Gross profit | -0.74M | 67.42M | -1.39M | - | - |
| Reconciled depreciation | 0.74M | 1.29M | 1.41M | 1.43M | 0.54M |
| Ebit | -145.01M | -187.46M | -248.99M | -227.29M | -216.54M |
| Ebitda | -144.27M | -186.17M | -247.60M | -233.27M | -268.52M |
| Depreciation and amortization | 0.74M | 1.29M | 1.39M | -5.99M | -51.98M |
| Non operating income net other | - | - | - | -16.28M | 49.75M |
| Operating income | -152.81M | -191.19M | -299.51M | -227.29M | -216.54M |
| Other operating expenses | 152.81M | 258.62M | 299.51M | 227.29M | 216.54M |
| Interest expense | - | - | - | 2.58M | 110.05M |
| Tax provision | 0.44M | 0.18M | -0.83M | -0.47M | -0.30M |
| Income tax expense | 0.44M | 0.18M | -0.60M | -0.47M | -0.30M |
| Total revenue | 0.00M | 67.42M | 0.00M | 0.00M | 0.00M |
| Total operating expenses | 152.81M | 258.62M | 299.51M | 227.29M | 216.54M |
| Cost of revenue | 0.74M | 1.29M | 1.39M | - | - |
| Total other income expense net | 16.19M | 25.50M | 6.60M | 5.99M | 51.98M |
| Net income from continuing ops | -137.06M | -165.87M | -286.35M | -220.83M | -164.26M |
| Net income applicable to common shares | - | - | - | -236.81M | -158.72M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 288.97M | 430.34M | 562.03M | 539.31M | 454.51M |
| Other current assets | 5.37M | 9.98M | 13.80M | 14.56M | 10.88M |
| Total liab | 72.76M | 93.15M | 124.64M | 105.29M | 90.03M |
| Total stockholder equity | 216.20M | 337.19M | 437.28M | 434.02M | 364.48M |
| Other current liab | 25.48M | 42.22M | 51.54M | 45.40M | 30.90M |
| Common stock | 0.07M | 0.07M | 0.07M | 0.06M | 0.04M |
| Capital stock | 0.07M | 0.07M | 0.07M | 0.06M | 0.04M |
| Retained earnings | -1191.45M | -1054.39M | -888.56M | -596.37M | -359.56M |
| Other liab | - | - | - | 3.47M | 1.62M |
| Good will | - | 0.00M | 3.74M | 3.74M | 3.74M |
| Other assets | - | - | - | 12.35M | 9.67M |
| Cash | 35.99M | 33.90M | 28.04M | 43.07M | 59.71M |
| Total current liabilities | 36.56M | 52.73M | 69.37M | 56.65M | 43.94M |
| Current deferred revenue | - | - | 0.28M | - | - |
| Net debt | 3.58M | 8.75M | 17.73M | 2.10M | -13.80M |
| Short term debt | 3.87M | 3.07M | 2.62M | - | 1.45M |
| Short long term debt total | 39.58M | 42.65M | 45.77M | 45.17M | 45.91M |
| Other stockholder equity | 1407.39M | 1390.95M | 1323.58M | 1031.68M | 724.12M |
| Property plant equipment | - | - | - | 7.71M | 8.15M |
| Total current assets | 253.19M | 386.07M | 496.72M | 451.93M | 350.77M |
| Long term investments | - | - | 0.00M | 21.21M | 37.49M |
| Net tangible assets | - | - | - | 433.80M | 360.22M |
| Short term investments | 209.90M | 337.18M | 454.88M | 394.30M | 280.17M |
| Net receivables | 1.93M | 5.00M | - | - | 4.44M |
| Inventory | - | - | - | - | -4.44M |
| Accounts payable | 7.21M | 7.44M | 14.93M | 11.25M | 11.59M |
| Noncontrolling interest in consolidated entity | - | - | - | 0.22M | 0.53M |
| Accumulated other comprehensive income | 0.20M | 0.56M | 2.19M | -1.35M | -0.12M |
| Common stock total equity | - | - | - | 0.06M | 0.04M |
| Retained earnings total equity | - | - | - | -596.37M | -359.56M |
| Non currrent assets other | 6.74M | 4.42M | 6.82M | 12.35M | 2.63M |
| Non current assets total | 35.78M | 44.27M | 65.31M | 87.38M | 103.74M |
| Capital lease obligations | 35.70M | 39.58M | 43.15M | 45.17M | 45.91M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | 130.93M | 176.56M | -14.29M | -111.63M | 2.31M |
| Change to liabilities | - | - | - | 15.53M | 13.92M |
| Total cashflows from investing activities | 131.62M | 176.56M | -44.46M | -114.18M | -18.11M |
| Total cash from financing activities | -4.28M | 0.11M | 237.30M | 261.04M | 178.52M |
| Change to operating activities | - | - | - | -2.27M | 2.23M |
| Net income | -137.06M | -165.87M | -292.19M | -237.11M | -166.09M |
| Change in cash | 2.09M | 5.81M | -14.98M | -16.89M | 6.31M |
| Begin period cash flow | 36.53M | 30.72M | 45.70M | 62.58M | 56.27M |
| End period cash flow | 38.62M | 36.53M | 30.72M | 45.70M | 62.58M |
| Total cash from operating activities | -125.25M | -170.86M | -207.82M | -163.75M | -154.09M |
| Issuance of capital stock | 5.69M | 0.35M | 287.04M | 261.04M | 179.67M |
| Depreciation | 0.74M | 1.29M | 1.39M | 1.43M | 0.54M |
| Other cashflows from investing activities | 0.70M | 0.07M | - | - | -14.32M |
| Change to inventory | - | - | - | - | 0.88M |
| Change to account receivables | 5.00M | -5.00M | 0.00M | - | 0.41M |
| Sale purchase of stock | -9.98M | 0.00M | 0.00M | 261.04M | 179.67M |
| Other cashflows from financing activities | - | -0.24M | -44.46M | -114.18M | -1.15M |
| Change to netincome | - | - | - | 62.41M | 46.38M |
| Capital expenditures | 0.00M | 0.22M | 0.58M | 2.55M | 6.11M |
| Change receivables | - | - | - | - | 0.41M |
| Cash flows other operating | - | - | - | -2.27M | -50.16M |
| Cash and cash equivalents changes | - | - | - | -16.89M | 6.31M |
| Change in working capital | -9.12M | -16.54M | 5.86M | 13.25M | 16.56M |
| Stock based compensation | 20.72M | 67.27M | 54.82M | 46.84M | 35.74M |
| Other non cash items | -0.53M | -57.01M | 23.15M | 12.61M | -38.38M |
| Free cash flow | -125.25M | -171.08M | -208.41M | -166.30M | -160.20M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| ZNTL Zentalis Pharmaceuticals Llc |
0.05 2.91% |
1.77 | - | - | 7.13 | 2.31 | 7.77 | -2.31 |
| NVO Novo Nordisk A/S |
1.03 2.56% |
41.34 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
1.49 0.27% |
548.58 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
18.16 2.01% |
922.51 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
Zentalis Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on discovering and developing small molecule therapeutics for the treatment of various cancers in the United States. It develops azenosertib, which is in a Phase 3 clinical trial for the treatment of ovarian cancer and other tumor types. The company also develops ZN-c3-001, a phase 1 study that evaluated azenosertib monotherapy in solid tumors; and MAMMOTH (ZN-c3-006) is a Phase 1/2 clinical trial of azenosertib in patients with PARP-inhibitor resistant ovarian cancer. It has licensing agreements and strategic collaborations with Recurium IP Holdings, LLC. Zentalis Pharmaceuticals, Inc. was incorporated in 2014 and is based in San Diego, California.
| Name | Title | Year Born |
|---|---|---|
| Dr. Kimberly Lynn Blackwell M.D. | CEO & Director | 1969 |
| Mr. Cameron S. Gallagher M.B.A. | Co-Founder, Pres & Director | 1970 |
| Dr. Kevin D. Bunker Ph.D. | Co-Founder & Chief Scientific Officer | 1972 |
| Ms. Melissa B. Epperly M.B.A. | CFO & Treasurer | 1978 |
| Adam Levy | Sr. VP of Investor Relations | NA |
| Ms. Andrea Paul J.D. | Gen. Counsel & Corp. Sec. | 1981 |
| Dr. Meena Rao Ph.D. | Sr. VP of Regulatory Affairs & Quality Assurance | NA |
| Dr. Carrie Brownstein M.D. | Chief Medical Officer | 1970 |
| Dr. Mark Lackner Ph.D. | Chief Translational Officer & Head of Biomarker Strategy | 1967 |
| Dr. Kimberly Lynn Blackwell M.D. | CEO & Director | 1970 |
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